We detect neuroinflammation biomarkers to decide which drug candidate moves forward.

Reproducible, longitudinal pharmacological profiles for CNS drug discovery.

Almost no Alzheimer's drug makes it to approval.

98%

Phase II/III failure rate in Alzheimer's over the last two decades

Kim et al., 2022

US$ 1.3B

Average cost to bring a drug to market

Wouters et al., 2020

US$ 250M/yr

Spent on failing anti-neuroinflammatory trials

Kim, 2022; Cummings et al., 2025

A market that keeps growing.

An aging population and regulation that favors human-relevant models.

US$ 27.6B

CNS drug discovery market by 2035

11%

Annual growth (CAGR) 2025-2035

Precedence Research

From cellular response to pharmacological profile.

  1. 1

    3D neuroglial model

    Astrocytes and microglia in 3D.

  2. 2

    Controlled perturbation

    Compound or inflammatory challenge.

  3. 3

    Longitudinal monitoring

    Specific biomarkers, tracked over time.

  4. 4

    Auditable profile

    Data for go/no-go decisions.

Our science is published, and regulation is moving our way.

Peer-reviewed Frontiers in Pharmacology | 2021

Pathological neuroinflammatory conversion of reactive astrocytes is induced by microglia and involves chromatin remodeling.

Villarreal A. et al.

Read the paper
Regulation FDA | 2022

FDA Modernization Act 2.0

Opens the door to human-relevant alternatives to animal testing.

From analytical service to data platform.

Pilot studies

Fee-for-service validation.

Recurring screening

Annual batch contracts.

Co-development

Custom, milestone-based.

Data & licensing

Proprietary database access.

Biology to decode the brain. Engineering to put it on a chip.

Javier Amado

Javier Amado

Co-founder | Microfluidics

Ex Stämm Biotech2 patents
LinkedIn
Alejandro Villarreal

Alejandro Villarreal

Neuroinflammation

PhD | H-index 19
LinkedIn
Gastón Corti

Gastón Corti

Devices & manufacturing

Ex Stämm Biotech1 patent
LinkedIn
Carolina Silveri

Carolina Silveri

Molecular biology

Bioengineering
LinkedIn
Victoria Mau

Victoria Mau

Engineering & development

Bioengineering
LinkedIn
The NiC team at Crossing Over 2026
Crossing Over 2026 | LATAM BioExpo | Buenos Aires

Want to learn more about our technology?

Talk directly with the founders.